Description

(4-Trifluoromethylphenoxy) Acetic Acid Ethyl Ester is a high-purity fluorinated organic building block essential for advanced chemical synthesis. This compound is valued for its trifluoromethylphenoxy moiety, which imparts unique electronic and steric properties to target molecules, enhancing their biological activity and metabolic stability. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where the trifluoromethyl group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic compounds for electronic materials, contributing to improved performance in display technologies.
• Advanced Polymer Chemistry: Employed as a monomer or modifier to introduce fluorine into polymer backbones, enhancing material properties like chemical resistance, thermal stability, and low surface energy.
• Chemical Research & Development: A versatile building block in academic and industrial R&D for exploring new reactions, catalytic processes, and structure-activity relationships (SAR).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale cGMP batches.

Basic Information

Product Name	(4-Trifluoromethylphenoxy) Acetic Acid Ethyl Ester
CAS No.	442125-30-6
Molecular Formula	C11H11F3O3
Molecular Weight	248.20 g/mol
Synonyms	Ethyl (4-(trifluoromethyl)phenoxy)acetate; Ethyl 2-[(4-trifluoromethyl)phenoxy]acetate; 4-Trifluoromethylphenoxyacetic Acid Ethyl Ester; Acetic acid, 2-[4-(trifluoromethyl)phenoxy]-, ethyl ester; α-((4-Trifluoromethyl)phenoxy)acetic Acid Ethyl Ester; p-Trifluoromethylphenoxyacetic Acid Ethyl Ester; Ethyl (p-Trifluoromethylphenoxy)acetate
EINECS	Contact for details

Quality Control

Our (4-Trifluoromethylphenoxy) Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.