Description

1(2H)-Pyrimidineacetic Acid, 4-[Bis[(1,1-Dimethylethoxy)Carbonyl]Amino]-2-Oxo- is a high-purity, protected amino acid derivative featuring a pyrimidine core, designed for advanced synthetic applications. This compound is a critical building block in pharmaceutical research and development, enabling the precise construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of potential drug candidates, particularly those targeting specific enzymatic pathways.
• Peptidomimetic Research: Serves as a non-natural amino acid analog for constructing modified peptides with enhanced stability or biological activity.
• Chemical Biology Probes: Used in the development of labeled compounds and probes for studying biological mechanisms and target engagement.
• Agrochemical Synthesis: Acts as a precursor in the research and development of new crop protection agents and herbicides.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new synthetic routes for heterocyclic compounds.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules at various scales under cGMP guidelines.

Basic Information

Product Name	1(2H)-Pyrimidineacetic Acid, 4-[Bis[(1,1-Dimethylethoxy)Carbonyl]Amino]-2-Oxo-
CAS No.	441780-11-6
Molecular Formula	C17H25N3O7
Molecular Weight	383.40 g/mol
Synonyms	4-[(Bis(tert-butoxycarbonyl)amino]-2-oxo-1,2-dihydropyrimidine-6-acetic acid; 4-(Di-Boc-amino)-2-oxo-1,2-dihydropyrimidine-6-acetic Acid; 4-[(Di-tert-butoxycarbonyl)amino]-2-oxo-1,2-dihydro-6-pyrimidineacetic acid; 4-(N,N-Di-Boc-amino)-2-oxo-1,2-dihydropyrimidine-6-acetic Acid; Boc-Protected 4-Aminopyrimidine Acetic Acid Derivative; 441780-11-6; tert-Butyl (6-carboxymethyl-2-oxo-1,2-dihydropyrimidin-4-yl)imidodicarbonate
EINECS	Contact for details

Quality Control

Every batch of our 1(2H)-Pyrimidineacetic Acid derivative is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development projects. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), impurity profile, and physical characteristics are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.