Description

2-(3-Methyl-Thiophen-2-Yl)-3-o-Tolyl-2,3-Dihydro-1H-Quinazolin-4-One is a high-value, complex heterocyclic compound that serves as a critical building block in advanced organic synthesis. This compound matters because it provides a sophisticated molecular scaffold essential for developing novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory activity.
• Agrochemical Research: Used as a core structure for developing new pesticides, herbicides, or fungicides with enhanced efficacy and selectivity.
• Material Science: Serves as a building block for creating advanced organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probe: Utilized in academic and industrial research to study biological pathways and protein interactions due to its unique fused-ring structure.
• Catalyst Ligand Development: The nitrogen and sulfur-containing heterocycle can be modified to create novel ligands for asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise molecular architecture.

Basic Information

Product Name	2-(3-Methyl-Thiophen-2-Yl)-3-o-Tolyl-2,3-Dihydro-1H-Quinazolin-4-One
CAS No.	440111-61-5
Molecular Formula	C20H18N2OS
Molecular Weight	334.44 g/mol
Synonyms	2-(3-Methyl-2-thienyl)-3-(2-methylphenyl)-2,3-dihydro-4(1H)-quinazolinone; 3-(2-Methylphenyl)-2-(3-methyl-2-thienyl)-1,2,3,4-tetrahydro-4-quinazolinone; 2,3-Dihydro-2-(3-methyl-2-thienyl)-3-(2-methylphenyl)-4(1H)-quinazolinone; 4(1H)-Quinazolinone, 2,3-dihydro-2-(3-methyl-2-thienyl)-3-(2-methylphenyl)-; 440111-61-5; Quinazolinone derivative with thiophene and toluene substituents; o-Tolyl quinazolinone thiophene derivative.
EINECS	Contact for details

Quality Control

Our 2-(3-Methyl-Thiophen-2-Yl)-3-o-Tolyl-2,3-Dihydro-1H-Quinazolin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.