Description

4-Bromo-2-Fluorobenzaldehyde Dimethyl Acetal is a high-purity, protected aldehyde derivative used as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those containing halogenated aromatic systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the bromo-fluoro substitution pattern imparts specific biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form complex biaryl structures.
• Protecting Group Strategy: The acetal group protects the aldehyde functionality during multi-step syntheses, allowing for selective reactions elsewhere on the molecule.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new chemical entities.

Basic Information

Product Name	4-Bromo-2-Fluorobenzaldehyde Dimethyl Acetal
CAS No.	439814-87-6
Molecular Formula	C9H10BrFO2
Molecular Weight	249.08 g/mol
Synonyms	1-Bromo-4-(dimethoxymethyl)-2-fluorobenzene; 2-Fluoro-4-bromobenzaldehyde dimethyl acetal; Benzaldehyde, 4-bromo-2-fluoro-, dimethyl acetal; (4-Bromo-2-fluorophenyl)dimethoxymethane; Dimethyl (4-bromo-2-fluorobenzylidene) acetal; 4-Bromo-2-fluorobenzaldehyde dimethyl acetal; 4-Bromo-2-fluoro-benzaldehyde dimethyl acetal
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorobenzaldehyde Dimethyl Acetal is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.