Description

(Rs)-1-[4-(Trifluoromethyl)Phenyl]Propylamine CAS NO 439811-20-8 is a chiral amine building block featuring a trifluoromethylphenyl group, a structural motif of high value in modern synthetic chemistry. This compound matters because it serves as a critical intermediate for the development of advanced pharmaceuticals and agrochemicals, where the trifluoromethyl group is prized for its ability to modulate lipophilicity, metabolic stability, and bioavailability. It is primarily needed by research and development chemists in the pharmaceutical industry for creating active pharmaceutical ingredients (APIs), as well as by agrochemical companies for novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the CF3 group enhances biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with unique electronic or surface properties.
• Chemical Biology Probes: Useful for creating molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	(Rs)-1-[4-(Trifluoromethyl)Phenyl]Propylamine
CAS No.	439811-20-8
Molecular Formula	C10H12F3N
Molecular Weight	203.20 g/mol
Synonyms	(R)-1-[4-(Trifluoromethyl)phenyl]propan-1-amine; (R)-α-Methyl-4-(trifluoromethyl)benzeneethanamine; (R)-1-(4-Trifluoromethylphenyl)propylamine; (R)-1-(4-(Trifluoromethyl)phenyl)propan-1-amine; (R)-4-(Trifluoromethyl)benzeneethanamine, α-methyl-; (R)-1-(4-CF3-Phenyl)propylamine; (R)-1-(p-Trifluoromethylphenyl)propylamine; (R)-TFPAmine
EINECS	Contact for details

Quality Control

Our (Rs)-1-[4-(Trifluoromethyl)Phenyl]Propylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with high-purity standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.