Description

4-Chloro-2-(Methylthio)-6-Thien-2-Ylpyrimidine-5-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique pyrimidine-thiophene hybrid structure, which serves as a critical scaffold for developing novel active compounds. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential kinase inhibitors, antiviral agents, and other biologically active small molecules.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a building block for creating functional organic materials, such as organic semiconductors or ligands for metal-organic frameworks (MOFs).
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and fine chemical manufacturers engaged in custom synthesis projects.

Basic Information

Product Name	4-Chloro-2-(Methylthio)-6-Thien-2-Ylpyrimidine-5-Carbonitrile
CAS No.	439808-45-4
Molecular Formula	C10H6ClN3S2
Molecular Weight	267.76 g/mol
Synonyms	4-Chloro-2-(methylsulfanyl)-6-(thiophen-2-yl)pyrimidine-5-carbonitrile; 6-(2-Thienyl)-4-chloro-2-(methylthio)-5-pyrimidinecarbonitrile; 4-Chloro-2-methylthio-6-(2-thienyl)pyrimidine-5-carbonitrile; 2-(Methylthio)-4-chloro-6-(thiophen-2-yl)pyrimidine-5-carbonitrile; CAS 439808-45-4
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-(Methylthio)-6-Thien-2-Ylpyrimidine-5-Carbonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.