Description

3'-Deoxy-3'-Fluoro-6-Azauridine is a fluorinated nucleoside analog of significant interest in pharmaceutical research and development. This compound is valued for its potential as a building block in the synthesis of novel antiviral and anticancer agents, leveraging its modified sugar moiety to influence biological activity and metabolic stability. It is primarily utilized by research institutions, biotechnology firms, and pharmaceutical companies engaged in drug discovery programs targeting viral infections and oncology.

Application

• Pharmaceutical Intermediate: Serves as a critical synthetic precursor in the development of novel nucleoside-based antiviral and anticancer therapeutics.
• Biochemical Research: Used as a tool compound in enzymatic studies to investigate the mechanisms of nucleoside metabolism and polymerase inhibition.
• Antiviral Agent Development: Explored for its potential activity against a range of RNA and DNA viruses due to its structural similarity to natural nucleosides.
• Oncology Research: Investigated for its antiproliferative properties and potential to be incorporated into prodrug strategies for targeted cancer therapy.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic and pharmacodynamic profiles of nucleoside analogs.

Basic Information

Product Name	3'-Deoxy-3'-Fluoro-6-Azauridine
CAS No.	439579-23-4
Molecular Formula	C9H11FN2O5
Molecular Weight	246.20 g/mol
Synonyms	3'-Fluoro-3'-deoxy-6-azauridine; 3'-Deoxy-3'-fluoro-6-azauridine; 6-Aza-3'-deoxy-3'-fluorouridine; 1-((2R,4S,5R)-4-Fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,2,4-triazine-3,5(2H,4H)-dione; 3'-F-6-AzaUrd
EINECS	Contact for details

Quality Control

Our 3'-Deoxy-3'-Fluoro-6-Azauridine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.