Description

Benzenamine,4-Fluoro-2-(Methylthio) CAS NO 439291-57-3 is a high-purity, fluorinated aniline derivative featuring a methylthio substituent, making it a versatile and valuable synthetic intermediate. Its unique structure provides a reactive amine group and a fluorine atom, enabling its use in the construction of complex molecules for advanced applications. This compound is primarily sought by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aromatic amine core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Dye and Pigment Chemistry: Acts as a precursor for the synthesis of specialized dyes and pigments, leveraging the amine group for coupling reactions.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) to create complex biaryl amines.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry teams exploring new synthetic pathways and molecular entities.

Basic Information

Product Name	Benzenamine,4-Fluoro-2-(Methylthio)
CAS No.	439291-57-3
Molecular Formula	C7H8FNS
Molecular Weight	157.21 g/mol
Synonyms	4-Fluoro-2-(methylthio)aniline; 2-(Methylthio)-4-fluoroaniline; 4-Fluoro-2-methylsulfanylaniline; 4-Fluoro-o-(methylthio)aniline; 2-Amino-5-fluorophenyl methyl sulfide; 5-Fluoro-2-aminophenyl methyl sulfide; Benzenamine, 4-fluoro-2-(methylthio)-; 4-Fluoro-2-(methylmercapto)aniline
EINECS	Contact for details

Quality Control

Every batch of Benzenamine,4-Fluoro-2-(Methylthio) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) specifying purity, identity, and impurity profiles is supplied with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.