Description

4-(2-[(4-Chlorobenzyl)Oxy]Phenyl)-2-(4-Pyridinyl)Pyrimidine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel therapeutic agents, particularly in kinase inhibitor research and development. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potential kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a reference standard or a ligand in enzymatic assays and structure-activity relationship (SAR) studies.
• Medicinal Chemistry: Serves as a core scaffold for the design and optimization of new chemical entities (NCEs) targeting specific protein kinases.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and drug discovery pathways.

Basic Information

Product Name	4-(2-[(4-Chlorobenzyl)Oxy]Phenyl)-2-(4-Pyridinyl)Pyrimidine
CAS No.	439109-62-3
Molecular Formula	C22H16ClN3O
Molecular Weight	373.84 g/mol
Synonyms	4-[2-[(4-Chlorophenyl)methoxy]phenyl]-2-(4-pyridinyl)pyrimidine; 2-(Pyridin-4-yl)-4-[2-[(4-chlorobenzyl)oxy]phenyl]pyrimidine; 4-(2-((4-Chlorobenzyl)oxy)phenyl)-2-(pyridin-4-yl)pyrimidine; CAS 439109-62-3; 4-(2-[(4-Chlorobenzyl)oxy]phenyl)-2-(4-pyridyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-(2-[(4-Chlorobenzyl)Oxy]Phenyl)-2-(4-Pyridinyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.