Description

1-[4-(2-Methyl-4-Pyrimidinyl)Phenyl]-1H-1,3-Benzimidazole is a high-purity, advanced pharmaceutical intermediate and research chemical of significant interest in modern organic synthesis. This compound, with CAS number 439108-63-1, is valued for its complex heterocyclic structure, which serves as a critical building block in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for projects targeting kinase inhibition and other therapeutic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted therapeutic agents, especially kinase inhibitors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or probe in biochemical assays to study specific enzyme interactions and cellular pathways.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to construct novel heterocyclic systems with potential biological activity.
• Academic Research: Utilized in university and institutional labs for advanced studies in heterocyclic chemistry and drug design methodologies.

Basic Information

Product Name	1-[4-(2-Methyl-4-Pyrimidinyl)Phenyl]-1H-1,3-Benzimidazole
CAS No.	439108-63-1
Molecular Formula	C18H14N4
Molecular Weight	286.33 g/mol
Synonyms	1-[4-(2-Methylpyrimidin-4-yl)phenyl]-1H-benzimidazole; 1-(4-(2-Methylpyrimidin-4-yl)phenyl)-1H-benzo[d]imidazole; 439108-63-1; UNII-8K5F1K5Q3I; Benzimidazole, 1-[4-(2-methyl-4-pyrimidinyl)phenyl]-; 8K5F1K5Q3I; 1-(4-(2-Methyl-4-pyrimidinyl)phenyl)benzimidazole
EINECS	Contact for details

Quality Control

Our 1-[4-(2-Methyl-4-Pyrimidinyl)Phenyl]-1H-1,3-Benzimidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.