Description

5-Propyl-2-[3-(1H-Pyrrol-1-Yl)-2-Thienyl]Pyrazolo[1,5-A]Pyrimidin-7-Ol CAS NO 439108-26-6 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and central nervous system (CNS) disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific biological pathways.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for drug discovery programs.
• Kinase Inhibitor Development: The pyrazolopyrimidine core is a privileged scaffold in the design of potent and selective kinase inhibitors for cancer therapy.
• Chemical Biology Probes: Employed in the development of molecular probes to study enzyme function and cellular signaling mechanisms.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial compounds for preclinical and clinical trials.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug design methodologies.

Basic Information

Product Name	5-Propyl-2-[3-(1H-Pyrrol-1-Yl)-2-Thienyl]Pyrazolo[1,5-A]Pyrimidin-7-Ol
CAS No.	439108-26-6
Molecular Formula	C17H16N4OS
Molecular Weight	324.40 g/mol
Synonyms	5-Propyl-2-[3-(1H-pyrrol-1-yl)-2-thienyl]pyrazolo[1,5-a]pyrimidin-7-ol; 7-Hydroxy-5-propyl-2-[3-(1H-pyrrol-1-yl)-2-thienyl]pyrazolo[1,5-a]pyrimidine; Pyrazolo[1,5-a]pyrimidin-7-ol, 5-propyl-2-[3-(1H-pyrrol-1-yl)-2-thienyl]-; CAS 439108-26-6
EINECS	Contact for details

Quality Control

Every batch of 5-Propyl-2-[3-(1H-Pyrrol-1-Yl)-2-Thienyl]Pyrazolo[1,5-A]Pyrimidin-7-Ol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards of pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your regulatory and research documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.