Description

6-(5-Chloro-2-Hydroxyphenyl)-2-Oxo-1,2,3,6-Tetrahydro-4-Pyrimidinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of new chemical entities (NCEs) for drug discovery.
• API Synthesis: Used as a building block in the multi-step synthesis of complex target molecules for potential therapeutic applications.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to develop compounds with optimized biological activity.
• Custom Synthesis: A vital component for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.
• Biochemical Research: May be utilized as a tool compound or inhibitor in biochemical assays and pharmacological studies.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	6-(5-Chloro-2-Hydroxyphenyl)-2-Oxo-1,2,3,6-Tetrahydro-4-Pyrimidinecarboxylic Acid
CAS No.	439095-04-2
Molecular Formula	C11H9ClN2O4
Molecular Weight	268.65 g/mol
Synonyms	4-Pyrimidinecarboxylic acid, 6-(5-chloro-2-hydroxyphenyl)-1,2,3,6-tetrahydro-2-oxo-; 6-(5-Chloro-2-hydroxyphenyl)-2-oxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid; 1,2,3,6-Tetrahydro-6-(5-chloro-2-hydroxyphenyl)-2-oxo-4-pyrimidinecarboxylic acid; CAS 439095-04-2
EINECS	Contact for details

Quality Control

Our 6-(5-Chloro-2-Hydroxyphenyl)-2-Oxo-1,2,3,6-Tetrahydro-4-Pyrimidinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.