Description

Elobixibat is a highly selective and potent ileal bile acid transporter (IBAT) inhibitor, a pharmaceutical active ingredient with the CAS registry number 439087-18-0. It is a critical compound for the development of treatments targeting chronic constipation and related gastrointestinal disorders. This API is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development and production of prescription medications.

Application

• Pharmaceutical API: Primary active ingredient in prescription drugs for the treatment of chronic idiopathic constipation (CIC).
• Clinical Research: Used in preclinical and clinical studies to investigate its efficacy and safety profile.
• Drug Formulation: Incorporated into solid oral dosage forms such as tablets and capsules.
• Gastrointestinal Therapeutics: Development of targeted therapies for disorders related to bile acid metabolism.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing.

Basic Information

Product Name	Elobixibat
CAS No.	439087-18-0
Molecular Formula	C29H32F3N3O4
Molecular Weight	543.58 g/mol
Synonyms	Elobixibat; A3309; 1-[[(4R)-4-[[(3S,5R)-3,5-Dimethyl-1-piperazinyl]carbonyl]-4-(4-fluorophenyl)-1-piperidinyl]methyl]-4-[(4-methyl-2-oxo-2H-1-benzopyran-7-yl)oxy]-1-azoniabicyclo[2.2.2]octane; (1R,4R,7S)-7-[[(4R)-4-[[(3S,5R)-3,5-Dimethylpiperazine-1-carbonyl]-4-(4-fluorophenyl)piperidin-1-yl]methyl]-1,4-epoxyazonane-1-ium-4-yl] 4-methyl-2-oxochromen-7-yl ether; Ileal Bile Acid Transporter (IBAT) Inhibitor A3309
EINECS	Contact for details

Quality Control

Our Elobixibat is manufactured under strict quality management systems, ensuring it meets the stringent requirements for pharmaceutical active ingredients. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) standards, and our quality protocols are designed to support regulatory filings in key global markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.