Description

3,5-Bis-(2,2,2-Trifluoro-Ethoxy)-Phenylamine is a high-purity, specialized aromatic amine derivative featuring trifluoroethoxy substituents, which impart unique electronic and steric properties. This compound is a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex organic molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for novel herbicides, fungicides, and insecticides, leveraging the stability of the trifluoroethoxy groups.
• Ligand & Catalyst Development: Used in organometallic chemistry to create specialized ligands for catalysis and material science applications.
• Functional Material Research: Intermediate for developing organic semiconductors, liquid crystals, and polymers with tailored electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.
• Academic & Industrial R&D: Employed in research laboratories for exploring new chemical entities and reaction pathways.

Basic Information

Item	Details
Product Name	3,5-Bis-(2,2,2-Trifluoro-Ethoxy)-Phenylamine
CAS No.	438530-76-8
Molecular Formula	C12H11F6NO2
Molecular Weight	315.21 g/mol
Synonyms	3,5-Bis(2,2,2-trifluoroethoxy)aniline; 3,5-Bis(2,2,2-trifluoroethoxy)benzenamine; 1-Amino-3,5-bis(2,2,2-trifluoroethoxy)benzene; 3,5-Di(2,2,2-trifluoroethoxy)phenylamine; 3,5-Bis(trifluoroethoxy)aniline; 3,5-Bis(2,2,2-trifluoroethoxy)phenylamine; Aniline, 3,5-bis(2,2,2-trifluoroethoxy)-
EINECS	Contact for details

Quality Control

Our 3,5-Bis-(2,2,2-Trifluoro-Ethoxy)-Phenylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and high-purity research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.