Description

6-(1-Fluoroethyl)-5-Iodo-4(1H)-Pyrimidinone is a high-value, halogenated pyrimidinone derivative, a key building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it an indispensable intermediate for creating novel compounds with targeted biological activity. This product is primarily required by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new active ingredients and for use in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel antiviral, anticancer, and other biologically active small molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its modifiable halogenated pyrimidine core.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new herbicides, fungicides, and pesticides.
• Chemical Biology Probes: Utilized in the development of molecular probes and diagnostic agents for biochemical research.
• Organic Synthesis Reagent: Acts as a versatile reagent for cross-coupling reactions and further functionalization in complex molecule assembly.

Basic Information

Product Name	6-(1-Fluoroethyl)-5-Iodo-4(1H)-Pyrimidinone
CAS No.	438449-92-4
Molecular Formula	C6H6FIN2O
Molecular Weight	268.03 g/mol
Synonyms	5-Iodo-6-(1-fluoroethyl)-4(1H)-pyrimidinone; 4(1H)-Pyrimidinone, 6-(1-fluoroethyl)-5-iodo-; 6-(1-Fluoroethyl)-5-iodo-1H-pyrimidin-4-one; 5-Iodo-6-(1-fluoroethyl)-1H-pyrimidin-4-one; 438449-92-4; CAS 438449-92-4
EINECS	Contact for details

Quality Control

Our 6-(1-Fluoroethyl)-5-Iodo-4(1H)-Pyrimidinone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.