Description

4-Chloro-2-Pyridin-2-Yl-6-Trifluoromethyl-Pyrimidine CAS NO 438249-84-4 is a high-value, multi-functional heterocyclic building block characterized by its pyrimidine core substituted with chloro, pyridinyl, and trifluoromethyl groups. This compound is essential for advanced organic synthesis, offering a versatile scaffold for constructing complex molecules with tailored properties. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine and trifluoromethyl motifs.
• Material Science: Serves as a building block for advanced organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Synthesis: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution, enabling diverse molecular diversification.
• Life Science Research: Employed as a biochemical tool or probe in academic and industrial research to study biological pathways and protein interactions.

Basic Information

Product Name	4-Chloro-2-Pyridin-2-Yl-6-Trifluoromethyl-Pyrimidine
CAS No.	438249-84-4
Molecular Formula	C10H5ClF3N3
Molecular Weight	259.62 g/mol
Synonyms	4-Chloro-2-(2-pyridinyl)-6-(trifluoromethyl)pyrimidine; 2-(4-Chloro-6-(trifluoromethyl)pyrimidin-2-yl)pyridine; 4-Chloro-2-pyridin-2-yl-6-(trifluoromethyl)pyrimidine; 438249-84-4; Pyrimidine, 4-chloro-2-(2-pyridinyl)-6-(trifluoromethyl)-; 4-Chloro-2-(pyridin-2-yl)-6-(trifluoromethyl)pyrimidine
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-2-Pyridin-2-Yl-6-Trifluoromethyl-Pyrimidine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Every lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.