Description

7-(Difluoromethyl)-5-Phenyl-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrimidine-3-Carbohydrazide is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers focused on developing new therapeutic and agrochemical agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, inflammatory diseases, and metabolic conditions.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating new generation pesticides and herbicides with improved efficacy.
• Chemical Biology Probe: Utilized in biochemical assays to study enzyme inhibition and protein-ligand interactions.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value compounds.

Basic Information

Product Name	7-(Difluoromethyl)-5-Phenyl-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrimidine-3-Carbohydrazide
CAS No.	438220-44-1
Molecular Formula	C₁₄H₁₅F₂N₅O
Molecular Weight	307.30 g/mol
Synonyms	5-Phenyl-7-(difluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carbohydrazide; 7-Difluoromethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylic acid hydrazide; Pyrazolo[1,5-a]pyrimidine-3-carbohydrazide, 4,5,6,7-tetrahydro-7-(difluoromethyl)-5-phenyl-; CAS 438220-44-1
EINECS	Contact for details

Quality Control

Our 7-(Difluoromethyl)-5-Phenyl-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrimidine-3-Carbohydrazide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to ensure traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.