Description

Ethyl 7-(Difluoromethyl)-5-Phenylpyrazolo[1,5-A]Pyrimidine-3-Carboxylate is a high-value, multi-functional heterocyclic building block. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, offering a versatile scaffold for medicinal chemistry. It is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation fungicides and herbicides due to its difluoromethyl and pyrazolopyrimidine motifs.
• Material Science Research: Serves as a specialized monomer or additive in the development of advanced organic electronic materials.
• Chemical Biology Probes: Employed in the design of fluorescent tags or activity-based probes for target identification and validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific, high-value target molecules.

Basic Information

Product Name	Ethyl 7-(Difluoromethyl)-5-Phenylpyrazolo[1,5-A]Pyrimidine-3-Carboxylate
CAS No.	438219-16-0
Molecular Formula	C₁₆H₁₃F₂N₃O₂
Molecular Weight	317.29 g/mol
Synonyms	7-(Difluoromethyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester; Ethyl 7-(difluoromethyl)-5-phenyl-1H-pyrazolo[1,5-a]pyrimidine-3-carboxylate; 5-Phenyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester; 438219-16-0; SCHEMBL21806227; ZINC000095909367; AKOS040759626; BDBM50389335
EINECS	Contact for details

Quality Control

Our Ethyl 7-(Difluoromethyl)-5-Phenylpyrazolo[1,5-A]Pyrimidine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.