Description

Ethyl 7-(Difluoromethyl)-5-Methylpyrazolo[1,5-A]Pyrimidine-3-Carboxylate is a high-value, functionalized pyrazolopyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the unique difluoromethyl and ester functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel drug candidates, particularly in kinase inhibitor research and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, where the pyrazolopyrimidine core can contribute to herbicidal or fungicidal activity.
• Chemical Biology Probe Development: Serves as a scaffold for creating tool compounds to study biological pathways and protein functions in academic and industrial research.
• Material Science Research: Potential building block for the synthesis of organic electronic materials or metal-organic frameworks (MOFs) due to its heterocyclic structure and functional groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects requiring this specific molecular motif.

Basic Information

Product Name	Ethyl 7-(Difluoromethyl)-5-Methylpyrazolo[1,5-A]Pyrimidine-3-Carboxylate
CAS No.	438218-16-7
Molecular Formula	C11H11F2N3O2
Molecular Weight	255.22 g/mol
Synonyms	Ethyl 7-(difluoromethyl)-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate; 7-(Difluoromethyl)-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 7-(difluoromethyl)-5-methyl-, ethyl ester; Ethyl 7-difluoromethyl-5-methyl-pyrazolo[1,5-a]pyrimidine-3-carboxylate; CAS 438218-16-7
EINECS	Contact for details

Quality Control

Our Ethyl 7-(Difluoromethyl)-5-Methylpyrazolo[1,5-A]Pyrimidine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC / MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.