Description

4(3H)-Quinazolinone, 2-Chloro-6-Iodo- is a halogenated quinazolinone derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and combinatorial chemistry libraries to explore new bioactive chemical space.
• Agrochemical Development: Acts as a building block for creating novel herbicides, fungicides, or plant growth regulators.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Material Science Research: Potential intermediate for the synthesis of organic electronic materials or metal-organic frameworks (MOFs) due to its heterocyclic structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development programs for global clients.

Basic Information

Product Name	4(3H)-Quinazolinone, 2-Chloro-6-Iodo-
CAS No.	438190-96-6
Molecular Formula	C8H4ClIN2O
Molecular Weight	306.49 g/mol
Synonyms	2-Chloro-6-iodoquinazolin-4(3H)-one; 2-Chloro-6-iodo-4(3H)-quinazolinone; 6-Iodo-2-chloro-3,4-dihydro-4-quinazolinone; 2-Chloro-6-iodo-3,4-dihydroquinazolin-4-one; Quinazolin-4(3H)-one, 2-chloro-6-iodo-; 2-Chloro-6-iodo-4-hydroxyquinazoline; 438190-96-6; 2-Cl-6-I-4-Quinazolinone
EINECS	Contact for details

Quality Control

Our 4(3H)-Quinazolinone, 2-Chloro-6-Iodo- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided and available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.