Description

2,6-Difluoro-4-Isopropyloxybenzyl Alcohol is a key fluorinated aromatic intermediate with significant utility in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and the reactive benzyl alcohol group, enabling precise molecular modifications. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the difluoro and isopropyloxy motifs contribute to enhanced biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays (LCDs) and optical devices.
• Organic Electronics: Employed in the research and production of materials for organic light-emitting diodes (OLEDs) and semiconductors, leveraging its electronic properties.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Protecting Group Chemistry: The benzyl alcohol functionality can be utilized in protective group strategies during multi-step synthetic sequences.

Basic Information

Item	Detail
Product Name	2,6-Difluoro-4-Isopropyloxybenzyl Alcohol
CAS No.	438049-80-0
Molecular Formula	C10H12F2O2
Molecular Weight	202.20 g/mol
Synonyms	4-(Isopropoxy)-2,6-difluorobenzyl Alcohol; 2,6-Difluoro-4-(1-methylethoxy)benzenemethanol; 2,6-Difluoro-4-isopropoxybenzyl Alcohol; (2,6-Difluoro-4-isopropoxyphenyl)methanol; Benzenemethanol, 2,6-difluoro-4-(1-methylethoxy)-; 438049-80-0; 2,6-Difluoro-4-(propan-2-yloxy)benzyl Alcohol
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-4-Isopropyloxybenzyl Alcohol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.