Description

Pyrimidin-2-Ylmethyl-Carbamic Acid tert-Butyl Ester is a high-purity chemical intermediate featuring a protected carbamate group. This compound is valued for its role as a versatile building block in the synthesis of complex organic molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing active pharmaceutical ingredients (APIs) and other specialty compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those containing pyrimidine scaffolds.
• Agrochemical Research: Used in the development of new pesticides and herbicides where the pyrimidine moiety is a critical functional group.
• Peptide Mimetics & PROTACs: Serves as a precursor for introducing protected amine functionalities into complex molecules like peptide mimetics and Proteolysis Targeting Chimeras (PROTACs).
• Chemical Biology Probes: Employed in the creation of molecular probes and labeled compounds for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific, high-purity intermediates.
• Academic Research: Utilized in university and institutional laboratories for methodological development and exploratory organic synthesis.

Basic Information

Product Name	Pyrimidin-2-Ylmethyl-Carbamic Acid tert-Butyl Ester
CAS No.	436161-78-3
Molecular Formula	C11H17N3O2
Molecular Weight	223.27 g/mol
Synonyms	tert-Butyl N-[(pyrimidin-2-yl)methyl]carbamate; N-(Pyrimidin-2-ylmethyl)carbamic Acid tert-Butyl Ester; 2-(((tert-Butoxycarbonyl)amino)methyl)pyrimidine; Boc-Pyrimidin-2-ylmethylamine; (Pyrimidin-2-ylmethyl)carbamic Acid 1,1-Dimethylethyl Ester; N-Boc-2-(Aminomethyl)pyrimidine; BOC-Aminomethylpyrimidine
EINECS	Contact for details

Quality Control

Our Pyrimidin-2-Ylmethyl-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.