Description

6-Amino-1-(2-Methoxyethyl)-2-Thioxo-2,3-Dihydropyrimidin-4(1H)-One CAS NO 436094-96-1 is a high-purity pyrimidinone derivative, a key heterocyclic building block valued for its unique thiocarbonyl and amino functionalities. This compound is critical for research and development in advanced organic synthesis, particularly in the creation of novel pharmacologically active molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for applications in medicinal chemistry and as a precursor for specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis due to its modifiable pyrimidinone core.
• Fine Chemical Synthesis: Acts as a precursor for the production of more complex heterocyclic compounds and specialty chemicals used in agrochemical and material science research.
• Biochemical Research: Potential use as a substrate or inhibitor in enzymatic studies, given its structural similarity to natural nucleobase analogs.
• Academic & Industrial R&D: Employed in exploratory chemistry for developing new synthetic methodologies and discovering compounds with novel biological activities.

Basic Information

Product Name	6-Amino-1-(2-Methoxyethyl)-2-Thioxo-2,3-Dihydropyrimidin-4(1H)-One
CAS No.	436094-96-1
Molecular Formula	C7H11N3O2S
Molecular Weight	201.25 g/mol
Synonyms	6-Amino-1-(2-methoxyethyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone; 6-Amino-1-(2-methoxyethyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone; 4(1H)-Pyrimidinone, 6-amino-1-(2-methoxyethyl)-2,3-dihydro-2-thioxo-; 6-Amino-1-(2-methoxyethyl)-2-thioxo-1,2-dihydropyrimidin-4-one; 2-Thioxo-6-amino-1-(2-methoxyethyl)-2,3-dihydro-4(1H)-pyrimidinone; 1-(2-Methoxyethyl)-6-amino-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone; 6-Amino-1-(2-methoxyethyl)-2-mercapto-4-pyrimidinol (tautomeric form); AMETP (common abbreviation)
EINECS	Contact for details

Quality Control

Our 6-Amino-1-(2-Methoxyethyl)-2-Thioxo-2,3-Dihydropyrimidin-4(1H)-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.