Description

5-Cyclopropyl-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its pyrazolopyrimidine core structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific therapeutic pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drugs, especially kinase inhibitors.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Oncology Drug Discovery: Serves as a core scaffold for developing targeted cancer therapies.
• Antiviral Agent Synthesis: Employed in the research and production of potential antiviral compounds.
• Chemical Biology Probes: Utilized to create specialized probes for studying enzyme function and cellular signaling pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	5-Cyclopropyl-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid
CAS No.	436088-48-1
Molecular Formula	C11H7F3N4O2
Molecular Weight	284.20 g/mol
Synonyms	5-Cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 5-Cyclopropyl-7-trifluoromethyl-2-pyrazolo[1,5-a]pyrimidinecarboxylic Acid; 7-(Trifluoromethyl)-5-cyclopropylpyrazolo[1,5-a]pyrimidine-2-carboxylic Acid; Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 5-cyclopropyl-7-(trifluoromethyl)-; CAS 436088-48-1
EINECS	Contact for details

Quality Control

Our 5-Cyclopropyl-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.