Description

6-(4,6-Dioxo-1,4,5,6-tetrahydro-pyrimidin-2-ylamino)-hexanoic acid is a high-purity, functionalized pyrimidine derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the development of novel compounds with potential biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of targeted small molecule libraries and the exploration of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the research and development of novel drug candidates, especially those targeting enzymes or receptors where the barbituric acid moiety is relevant.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing diverse compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Bioconjugation & Probe Development: The carboxylic acid functional group allows for coupling to amines, making it useful for creating fluorescent probes, affinity labels, or protein conjugates for biochemical research.
• Academic & Institutional R&D: Employed in synthetic organic chemistry projects focused on heterocyclic compounds, peptidomimetics, and the development of new synthetic methodologies.
• Chemical Biology: Serves as a tool compound for investigating biological pathways and interactions due to its potential to mimic natural substrates or inhibitors.

Basic Information

Product Name	6-(4,6-Dioxo-1,4,5,6-tetrahydro-pyrimidin-2-ylamino)-hexanoic Acid
CAS No.	435345-32-7
Molecular Formula	C10H15N3O4
Molecular Weight	241.25 g/mol
Synonyms	6-[(4,6-Dioxo-1,4,5,6-tetrahydro-2-pyrimidinyl)amino]hexanoic acid; 2-Amino-4,6-dihydroxypyrimidine-6-hexanoic acid; N-(1,4,5,6-Tetrahydro-4,6-dioxo-2-pyrimidinyl)-6-aminohexanoic acid; 6-(4,6-Dihydroxy-2-pyrimidinylamino)hexanoic acid; 6-(2-Amino-4,6-dioxo-1,4,5,6-tetrahydropyrimidin-1-yl)hexanoic acid; Barbituric acid, 2-(6-carboxyhexyl)amino-; Hexanoic acid, 6-[(4,6-dioxo-1,4,5,6-tetrahydro-2-pyrimidinyl)amino]-
EINECS	Contact for details

Quality Control

Our 6-(4,6-Dioxo-1,4,5,6-tetrahydro-pyrimidin-2-ylamino)-hexanoic acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Products undergo rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.