Description

2-(4-Oxo-4H-Quinazolin-3-Yl)-Propionic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its quinazolinone core structure. This compound is critical for the research and development of novel therapeutic agents, particularly in oncology and other disease areas. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new chemical entities.
• Biochemical Research: Employed as a tool compound or probe in enzymatic assays and biological pathway studies.
• Fine Chemical Synthesis: Acts as a precursor for the preparation of more complex, functionalized quinazolinone derivatives.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	2-(4-Oxo-4H-Quinazolin-3-Yl)-Propionic Acid
CAS No.	435345-19-0
Molecular Formula	C₁₁H₁₀N₂O₃
Molecular Weight	218.21 g/mol
Synonyms	3-(2-Carboxyethyl)-4(3H)-quinazolinone; 2-(4-Oxo-3,4-dihydroquinazolin-3-yl)propanoic acid; 3-(2-Carboxyethyl)quinazolin-4(3H)-one; 2-(4-Oxo-4H-quinazolin-3-yl)propionic acid; Propanoic acid, 2-(4-oxo-3,4-dihydro-2-quinazolinyl)-; Quinazolinone propionic acid derivative
EINECS	Contact for details

Quality Control

Our 2-(4-Oxo-4H-Quinazolin-3-Yl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) documenting all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.