Description

2-[(6-Methoxy-4-Methylquinazolin-2-Yl)Amino]-6-Oxo-n-Phenyl-1,4,5,6-Tetrahydropyrimidine-4-Carboxamide is a high-purity, complex heterocyclic organic compound serving as a critical advanced intermediate in pharmaceutical research and development. Its molecular architecture makes it a valuable scaffold for medicinal chemists exploring novel therapeutic agents. This compound is primarily utilized by R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in oncology and other targeted therapy areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Kinase Inhibitor Development: Serves as a precursor in the synthesis of potential kinase inhibitors due to its quinazoline and tetrahydropyrimidine motifs.
• Contract Research & Development (CRO): Supplied to CROs and academic institutions for exploratory life science research.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to create more complex, target-specific molecules.
• Reference Standard: Can be used as a high-purity analytical standard for method development and quality control.

Basic Information

Product Name	2-[(6-Methoxy-4-Methylquinazolin-2-Yl)Amino]-6-Oxo-n-Phenyl-1,4,5,6-Tetrahydropyrimidine-4-Carboxamide
CAS No.	434313-00-5
Molecular Formula	C21H20N6O3
Molecular Weight	404.42 g/mol
Synonyms	2-[(6-Methoxy-4-methylquinazolin-2-yl)amino]-6-oxo-N-phenyl-1,4,5,6-tetrahydropyrimidine-4-carboxamide; 4-Carboxamide-2-[(6-methoxy-4-methyl-2-quinazolinyl)amino]-6-oxo-N-phenyl-1,4,5,6-tetrahydropyrimidine; 434313-00-5; UNII-1V6W3X3Q4N; 1V6W3X3Q4N; 2-((6-Methoxy-4-methylquinazolin-2-yl)amino)-6-oxo-N-phenyl-1,4,5,6-tetrahydropyrimidine-4-carboxamide
EINECS	Contact for details

Quality Control

Our 2-[(6-Methoxy-4-Methylquinazolin-2-Yl)Amino]-6-Oxo-n-Phenyl-1,4,5,6-Tetrahydropyrimidine-4-Carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.