Description

3-Chloro-5-(Difluoromethoxy)Benzaldehyde (Wxg00816) is a high-purity, multi-functional aromatic aldehyde building block. This compound is valued for its unique halogenated and difluoromethoxy-substituted structure, which imparts specific electronic and steric properties critical for advanced synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the difluoromethoxy group for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals and organic semiconductors, where its specific substitution pattern fine-tunes material properties.
• Custom Synthesis and Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Chloro-5-(Difluoromethoxy)Benzaldehyde (Wxg00816)
CAS No.	433940-20-6
Molecular Formula	C8H5ClF2O2
Molecular Weight	206.57 g/mol
Synonyms	3-Chloro-5-(difluoromethoxy)benzaldehyde; Benzaldehyde, 3-chloro-5-(difluoromethoxy)-; 5-(Difluoromethoxy)-3-chlorobenzaldehyde; WXG00816; Wxg00816
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-(Difluoromethoxy)Benzaldehyde is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) including purity (HPLC/GC), identity confirmation (IR, NMR), and impurity profile is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.