Description

3-Fluoro-5-Bromophenol is a halogenated phenol derivative that serves as a versatile and high-value building block in advanced organic synthesis. Its unique structure, featuring both fluorine and bromine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing fluorinated and brominated aromatic cores essential in electronic materials for displays and lighting.
• Polymer Chemistry: Acts as a monomer or functionalization agent for creating specialty polymers with specific thermal, optical, or chemical resistance properties.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings, enabling rapid diversification of molecular scaffolds.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3-Fluoro-5-Bromophenol
CAS No.	433939-27-6
Molecular Formula	C6H4BrFO
Molecular Weight	191.00 g/mol
Synonyms	5-Bromo-3-fluorophenol; 3-Bromo-5-fluorophenol; Phenol, 3-bromo-5-fluoro-; 3-Fluoro-5-bromo-1-hydroxybenzene; 1-Bromo-3-fluoro-5-hydroxybenzene; 3-F-5-Br-PhOH; 3F5BrPhOH
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-Bromophenol is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality system supports development and commercial supply, from milligram to kilogram scales, with a focus on reproducibility and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its phenolic nature and light sensitivity, prolonged exposure to light or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.