Description

5-(4-Chlorophenyl)-4-(4-(3-Fluoro-4-methoxybenzyl)piperazin-1-yl)thieno[2,3-d]pyrimidine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel therapeutic agents. This compound is critical for medicinal chemistry research and development, offering a sophisticated heterocyclic scaffold for targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing kinase inhibitors and other small molecule therapeutics.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in vitro to study specific biological pathways and enzyme interactions.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex, target-specific drug candidates.
• Contract Research & Development (CRO): Supplied to organizations specializing in custom synthesis and preclinical development.

Basic Information

Product Name	5-(4-Chlorophenyl)-4-(4-(3-Fluoro-4-methoxybenzyl)piperazin-1-yl)thieno[2,3-d]pyrimidine
CAS No.	433703-21-0
Molecular Formula	C24H22ClFN4OS
Molecular Weight	468.97 g/mol
Synonyms	Thieno[2,3-d]pyrimidine, 5-(4-chlorophenyl)-4-[4-[(3-fluoro-4-methoxyphenyl)methyl]-1-piperazinyl]-; BMS-599626; BMS599626; 4-(4-(3-Fluoro-4-methoxybenzyl)piperazin-1-yl)-5-(4-chlorophenyl)thieno[2,3-d]pyrimidine; AC1L4BUK; AC-1L4BUK; CHEMBL1233455; AKOS015903065
EINECS	Contact for details

Quality Control

Our 5-(4-Chlorophenyl)-4-(4-(3-Fluoro-4-methoxybenzyl)piperazin-1-yl)thieno[2,3-d]pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.