Description

5-(4-Chlorophenyl)-n-(4-Fluorophenyl)Thieno[2,3-D]Pyrimidin-4-Amine is a high-purity, heterocyclic organic compound belonging to the thienopyrimidine class. This advanced pharmaceutical intermediate is valued for its role in the research and development of novel therapeutic agents, particularly kinase inhibitors. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology firms, and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a reference standard or probe molecule in enzymatic assays and structure-activity relationship (SAR) studies.
• Organic Synthesis: Serves as a versatile scaffold for medicinal chemists to develop new chemical entities with potential biological activity.
• Preclinical Development: Employed in the preparation of candidate drug compounds for pharmacological and toxicological evaluation.
• Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic chemistry and drug discovery.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	5-(4-Chlorophenyl)-n-(4-Fluorophenyl)Thieno[2,3-D]Pyrimidin-4-Amine
CAS No.	433696-97-0
Molecular Formula	C18H11ClFN3S
Molecular Weight	355.81 g/mol
Synonyms	4-Amino-5-(4-chlorophenyl)-N-(4-fluorophenyl)thieno[2,3-d]pyrimidine; 5-(4-Chlorophenyl)-N-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-amine; Thieno[2,3-d]pyrimidin-4-amine, 5-(4-chlorophenyl)-N-(4-fluorophenyl)-; 433696-97-0; 5-(p-Chlorophenyl)-N-(p-fluorophenyl)thieno[2,3-d]pyrimidin-4-amine; N-(4-Fluorophenyl)-5-(4-chlorophenyl)thieno[2,3-d]pyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our 5-(4-Chlorophenyl)-n-(4-Fluorophenyl)Thieno[2,3-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.