Description

5-Bromo-2-(Isopropylthio)Pyrimidine is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its reactive bromine and thioether functionalities, enabling precise molecular construction. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions for introducing the pyrimidine moiety.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	5-Bromo-2-(Isopropylthio)Pyrimidine
CAS No.	433684-22-1
Molecular Formula	C7H9BrN2S
Molecular Weight	233.13 g/mol
Synonyms	5-Bromo-2-(isopropylsulfanyl)pyrimidine; 2-Isopropylthio-5-bromopyrimidine; 5-Bromo-2-(1-methylethylthio)pyrimidine; 433684-22-1; 5-Bromo-2-(propan-2-ylsulfanyl)pyrimidine; Pyrimidine, 5-bromo-2-[(1-methylethyl)thio]-; 5-Bromo-2-isopropylthiopyrimidine
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-(Isopropylthio)Pyrimidine is manufactured and tested under a strict quality management system. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via HPLC, GC, NMR, and IR is provided with each shipment to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.