Description

5-Pyrimidinecarboxamide,1,2,3,4-Tetrahydro-N,6-Dimethyl-2-Oxo-4-(2-Thienyl)-(9Ci) is a high-purity, heterocyclic organic compound featuring a fused pyrimidine and thiophene ring system, serving as a critical advanced pharmaceutical intermediate for modern drug discovery and development. Its unique molecular architecture makes it a valuable scaffold for medicinal chemistry, enabling the synthesis of novel therapeutic agents targeting a range of diseases. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small-molecule drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Serves as a privileged scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries.
• Agrochemical Development: Used in the research and synthesis of new generation pesticides and herbicides, leveraging its heterocyclic bioactivity.
• Fine Chemical Synthesis: Intermediate for creating complex, high-value specialty chemicals used in electronics and material science.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and research institutions for custom synthesis and process development projects.
• Academic Research: Utilized in university and institutional labs for organic synthesis methodology development and biochemical studies.

Basic Information

Product Name	5-Pyrimidinecarboxamide,1,2,3,4-Tetrahydro-N,6-Dimethyl-2-Oxo-4-(2-Thienyl)-(9Ci)
CAS No.	433320-81-1
Molecular Formula	C11H13N3O2S
Molecular Weight	251.30 g/mol
Synonyms	4-(Thiophen-2-yl)-1,2,3,4-tetrahydro-N,6-dimethyl-2-oxopyrimidine-5-carboxamide; 4-(2-Thienyl)-1,2,3,4-tetrahydro-N,6-dimethyl-2-oxo-5-pyrimidinecarboxamide; 5-Pyrimidinecarboxamide, 1,2,3,4-tetrahydro-N,6-dimethyl-2-oxo-4-(2-thienyl)-; 4-(2-Thienyl)-N,6-dimethyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxamide; CAS 433320-81-1
EINECS	Contact for details

Quality Control

Our 5-Pyrimidinecarboxamide derivative is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical parameters such as assay and impurity profiles. Our production adheres to cGMP principles where required, ensuring suitability for demanding pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.