Description

Benzenemethanol, 3,5-Difluoro-α-Methyl-, (Alphar)- (9Ci) is a chiral fluorinated benzyl alcohol derivative, serving as a valuable advanced pharmaceutical intermediate (API) and a versatile building block in synthetic organic chemistry. Its molecular architecture, featuring a stereogenic center and fluorine substituents, is critical for modulating the biological activity, metabolic stability, and lipophilicity of target molecules. This compound is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Building block for developing novel fluorinated pesticides and herbicides, where fluorine atoms enhance compound efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Used in the synthesis of fluorinated aromatic components for advanced electronic display and lighting materials.
• Asymmetric Catalysis & Ligand Development: Serves as a precursor for chiral ligands and auxiliaries used in enantioselective synthesis.
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) and new fluorination methodologies in academic and industrial labs.
• Fine Chemical Manufacturing: Intermediate for producing specialty chemicals, flavors, fragrances, and other high-value-added products.

Basic Information

Product Name	Benzenemethanol, 3,5-Difluoro-α-Methyl-, (Alphar)- (9Ci)
CAS No.	433228-88-7
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	(αR)-3,5-Difluoro-α-methylbenzenemethanol; (R)-3,5-Difluoro-α-methylbenzyl alcohol; (R)-1-(3,5-Difluorophenyl)ethanol; (R)-α-Methyl-3,5-difluorobenzyl alcohol; 3,5-Difluoro-α-methyl-benzyl alcohol (R)-; (R)-(3,5-Difluorophenyl)ethanol; (R)-3,5-Difluoro-α-methyl-benzenemethanol; Benzenemethanol, 3,5-difluoro-α-methyl-, (αR)-
EINECS	Contact for details

Quality Control

Our production of Benzenemethanol, 3,5-Difluoro-α-Methyl-, (Alphar)- (9Ci) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure consistent chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.