Description

3-(4-Fluorobenzyl)-2-Sulfanylquinazolin-4(3H)-One is a specialized quinazolinone derivative, a high-value chemical intermediate of significant interest in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which incorporates both a fluorinated benzyl group and a sulfanyl moiety, making it a versatile building block for creating novel compounds. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those focused on developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) agents, kinase inhibitors, and other therapeutic small molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinazolinone core.
• Material Science: Serves as a building block for advanced organic materials, such as ligands for catalysis or components in organic electronic devices.
• Chemical Biology & Proteomics: Employed as a scaffold or probe in biochemical research to study enzyme inhibition and protein-ligand interactions.
• Academic & Contract Research: A critical reagent for universities and CROs (Contract Research Organizations) conducting exploratory synthetic chemistry and medicinal chemistry programs.

Basic Information

Product Name	3-(4-Fluorobenzyl)-2-Sulfanylquinazolin-4(3H)-One
CAS No.	431980-10-8
Molecular Formula	C15H11FN2OS
Molecular Weight	286.33 g/mol
Synonyms	3-[(4-Fluorophenyl)methyl]-2-sulfanyl-4(3H)-quinazolinone; 3-(4-Fluorobenzyl)-2-mercaptoquinazolin-4(3H)-one; 2-Mercapto-3-(4-fluorobenzyl)-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 3-[(4-fluorophenyl)methyl]-2-thioxo-; 431980-10-8; 3-(p-Fluorobenzyl)-2-thioxo-1,2,3,4-tetrahydroquinazolin-4-one
EINECS	Contact for details

Quality Control

Our production of 3-(4-Fluorobenzyl)-2-Sulfanylquinazolin-4(3H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.