Description

Allyl 6-(3,4-Dimethoxyphenyl)-8-Methyl-4-Oxo-3,4-Dihydro-2H,6H-Pyrimido[2,1-B][1,3]Thiazine-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by research institutions, custom synthesis laboratories, and pharmaceutical companies engaged in the development of new chemical entities and proprietary drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of target drug molecules, especially those with fused pyrimidothiazine cores.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Development: Employed in the process research and development (PR&D) and scale-up phases for new active pharmaceutical ingredients.
• Custom Synthesis: Supplied to contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.
• Biochemical Tool Compound: Potential use in developing probes for investigating biological pathways and target validation.

Basic Information

Product Name	Allyl 6-(3,4-Dimethoxyphenyl)-8-Methyl-4-Oxo-3,4-Dihydro-2H,6H-Pyrimido[2,1-B][1,3]Thiazine-7-Carboxylate
CAS No.	431941-61-6
Molecular Formula	C20H22N2O5S
Molecular Weight	402.46 g/mol
Synonyms	Allyl 6-(3,4-dimethoxyphenyl)-8-methyl-4-oxo-3,4-dihydro-2H,6H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate; 2H,6H-Pyrimido[2,1-b][1,3]thiazine-7-carboxylic acid, 6-(3,4-dimethoxyphenyl)-3,4-dihydro-8-methyl-4-oxo-, allyl ester; Allyl 6-(3,4-dimethoxyphenyl)-8-methyl-4-oxo-3,4,6,7-tetrahydropyrimido[2,1-b][1,3]thiazine-7-carboxylate; CAS 431941-61-6
EINECS	Contact for details

Quality Control

Our Allyl 6-(3,4-Dimethoxyphenyl)-8-Methyl-4-Oxo-3,4-Dihydro-2H,6H-Pyrimido[2,1-B][1,3]Thiazine-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.