Description

Methanediol, (4-Fluoro-3-Methylphenyl)- (9Ci) is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a critical strategy for modulating biological activity and stability. Industries requiring high-purity, custom synthetic intermediates for research and development, including pharmaceutical R&D, agrochemical formulation, and advanced material science, are the primary users of this product.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine moiety enhances product efficacy and environmental stability.
• Advanced Material Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers, coatings, and liquid crystal materials requiring specific fluorinated aromatic structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new organic reactions, catalytic processes, and the creation of compound libraries for high-throughput screening.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP or research-grade conditions.

Basic Information

Product Name	Methanediol, (4-Fluoro-3-Methylphenyl)- (9Ci)
CAS No.	430431-53-1
Molecular Formula	C9H10FO2
Molecular Weight	169.17 g/mol
Synonyms	(4-Fluoro-3-methylphenyl)methanediol; 1-(4-Fluoro-3-methylphenyl)methane-1,1-diol; 4-Fluoro-3-methylbenzaldehyde hydrate; α,α-Dihydroxy-4-fluoro-3-methyltoluene; 4-Fluoro-3-methylbenzaldehyde dihydrate; (4-Fluoro-3-methylbenzyl) glycol; 430431-53-1
EINECS	Contact for details

Quality Control

Our Methanediol, (4-Fluoro-3-Methylphenyl)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with relevant regulatory frameworks, including REACH, and can tailor specifications to meet specific research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali conditions and should be stored separately from such materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.