Description

4-(3-Methoxyphenyl)-3,4,5,6-Tetrahydrobenzo[H]Quinazoline-2-Thiol is a high-purity, specialized heterocyclic organic compound with a quinazoline-thiol core structure. This advanced chemical intermediate is valued for its unique molecular architecture, which makes it a critical building block in sophisticated organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic scaffold for bioactivity.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to construct fused polycyclic systems due to its reactive thiol and quinazoline functionalities.
• Material Science Research: Investigated as a potential ligand for metal-organic frameworks (MOFs) or as a monomer for specialty polymers with specific electronic or binding properties.
• Biochemical Probe Development: Utilized in academic and industrial research to create molecular probes for studying enzyme inhibition or protein-ligand interactions.

Basic Information

Product Name	4-(3-Methoxyphenyl)-3,4,5,6-Tetrahydrobenzo[H]Quinazoline-2-Thiol
CAS No.	425647-07-0
Molecular Formula	C19H18N2OS
Molecular Weight	322.42 g/mol
Synonyms	4-(3-Methoxyphenyl)-3,4,5,6-tetrahydro-2-thioxo-1H-benzo[h]quinazoline; 4-(3-Methoxyphenyl)-1,4,5,6-tetrahydrobenzo[h]quinazoline-2-thiol; 2-Thioxo-4-(3-methoxyphenyl)-1,2,3,4,5,6-hexahydrobenzo[h]quinazoline; Benzo[h]quinazoline-2-thiol, 3,4,5,6-tetrahydro-4-(3-methoxyphenyl)-; 425647-07-0; 4-(3-Methoxyphenyl)-3,4,5,6-tetrahydrobenzo[h]quinazoline-2(1H)-thione
EINECS	Contact for details

Quality Control

Our production of 4-(3-Methoxyphenyl)-3,4,5,6-Tetrahydrobenzo[H]Quinazoline-2-Thiol adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.