Description

1H-Indole-3-Acetic Acid, 7-Fluoro-A-Oxo-, Methyl Ester is a high-purity, fluorinated indole derivative, a key advanced intermediate in modern organic synthesis. This compound matters for its precise molecular architecture, offering a versatile scaffold for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine atoms and specific ester functionalities into complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators with enhanced activity and selectivity.
• Chemical Biology Probe: Acts as a precursor for fluorescent tags or molecular probes to study biological pathways and enzyme functions.
• Material Science: Employed in the research of advanced organic electronic materials and liquid crystals due to its indole core and fluorinated structure.
• Academic & Contract Research: Essential for methodology development and synthetic chemistry research in universities and CROs (Contract Research Organizations).

Basic Information

Product Name	1H-Indole-3-Acetic Acid, 7-Fluoro-A-Oxo-, Methyl Ester
CAS No.	425638-75-1
Molecular Formula	C12H10FNO3
Molecular Weight	235.21 g/mol
Synonyms	7-Fluoro-1H-indole-3-acetic acid α-oxo-methyl ester; Methyl 2-(7-fluoro-1H-indol-3-yl)-2-oxoacetate; 7-Fluoroindole-3-glyoxylic acid methyl ester; 7-Fluoro-3-indolylglyoxylic acid methyl ester; 7-Fluoro-α-oxo-1H-indole-3-acetic acid methyl ester; 7-Fluoro-1H-indole-3-glyoxylic acid methyl ester; Methyl (7-fluoro-1H-indol-3-yl)oxoacetate
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Acetic Acid, 7-Fluoro-A-Oxo-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP (current Good Manufacturing Practice) compliance for use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.