Description

4-Chloro-5-Cyano-6-Methylpyrimidine is a high-value, multi-functional heterocyclic building block with the CAS registry number 425395-73-9. This compound is prized for its reactive chloro and cyano substituents, which make it a versatile intermediate for constructing complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, tags, and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological development and exploring new chemical reactions.

Basic Information

Product Name	4-Chloro-5-Cyano-6-Methylpyrimidine
CAS No.	425395-73-9
Molecular Formula	C6H4ClN3
Molecular Weight	153.57 g/mol
Synonyms	4-Chloro-6-methylpyrimidine-5-carbonitrile; 6-Methyl-4-chloropyrimidine-5-carbonitrile; 5-Cyano-4-chloro-6-methylpyrimidine; 4-Chloro-6-methyl-5-pyrimidinecarbonitrile; 4-Chloro-5-cyano-6-methyl-pyrimidine; Pyrimidine, 4-chloro-5-cyano-6-methyl-
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Cyano-6-Methylpyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.