Description

4-Chloro-5-Cyano-6-Difluoromethylpyrimidine is a high-purity, multi-functional pyrimidine derivative serving as a critical building block in advanced chemical synthesis. This compound is valued for its unique halogenated and nitrile-substituted structure, which enables precise molecular modifications. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of antiviral, anticancer, and other biologically active small-molecule drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for functional materials, including liquid crystals and organic semiconductors.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom chemical synthesis and scale-up projects.
• Academic & Industrial R&D: Employed in medicinal chemistry and process chemistry research for structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Chloro-5-Cyano-6-Difluoromethylpyrimidine
CAS No.	425394-90-7
Molecular Formula	C6H2ClF2N3
Molecular Weight	189.55 g/mol
Synonyms	6-(Difluoromethyl)-4-chloro-5-pyrimidinecarbonitrile; 4-Chloro-6-(difluoromethyl)pyrimidine-5-carbonitrile; 4-Chloro-5-cyano-6-(difluoromethyl)pyrimidine; Pyrimidine, 4-chloro-5-cyano-6-(difluoromethyl)-; 425394-90-7
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-5-Cyano-6-Difluoromethylpyrimidine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.