Description

5-Chloro-4-Hydroxy-2-Methyl-6-Trifluoromethyl-Pyrimidine is a high-value, multi-functional heterocyclic building block. This compound is critical for the synthesis of advanced agrochemicals and pharmaceuticals, where its unique trifluoromethyl and chloro substituents impart desirable biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for creating novel active ingredients and intermediates.

Application

• Agrochemical Intermediate: A key synthon for developing next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing trifluoromethyl group.
• Pharmaceutical Building Block: Used in medicinal chemistry for the research and synthesis of novel drug candidates, particularly in antiviral and anticancer therapeutic areas.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex, fluorinated pyrimidine derivatives for specialized chemical applications.
• Material Science Research: Investigated as a monomer or additive for developing advanced polymers and functional materials with specific electronic or surface properties.

Basic Information

Product Name	5-Chloro-4-Hydroxy-2-Methyl-6-Trifluoromethyl-Pyrimidine
CAS No.	425394-36-1
Molecular Formula	C6H3ClF3N2O
Molecular Weight	226.55 g/mol
Synonyms	5-Chloro-2-methyl-4-hydroxy-6-(trifluoromethyl)pyrimidine; 4-Hydroxy-5-chloro-2-methyl-6-trifluoromethylpyrimidine; 2-Methyl-5-chloro-4-hydroxy-6-trifluoromethylpyrimidine; 6-Trifluoromethyl-5-chloro-4-hydroxy-2-methylpyrimidine; 5-Chloro-4-hydroxy-2-methyl-6-(trifluoromethyl)pyrimidine; 425394-36-1; 5-Chloro-4-hydroxy-2-methyl-6-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-Hydroxy-2-Methyl-6-Trifluoromethyl-Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.