Description

4,5-Dichloro-2-Methyl-6-Trifluoromethylpyrimidine is a high-purity halogenated pyrimidine building block of significant importance in advanced organic synthesis. Its core value lies in its unique trifluoromethyl and chloro substituents, which are critical for modulating the physicochemical properties of target molecules, particularly in enhancing metabolic stability and lipophilicity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential herbicides, fungicides, and pharmaceutical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas requiring fluorinated heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides due to its bioactive pyrimidine core.
• Chemical Research & Development: Serves as a versatile building block in organic chemistry for constructing complex, multi-substituted heterocyclic systems.
• Material Science Precursor: Potential use in the synthesis of specialty chemicals and functional materials that incorporate fluorine.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	4,5-Dichloro-2-Methyl-6-Trifluoromethylpyrimidine
CAS No.	425394-33-8
Molecular Formula	C6H3Cl2F3N2
Molecular Weight	231.00 g/mol
Synonyms	2-Methyl-4,5-dichloro-6-(trifluoromethyl)pyrimidine; 4,5-Dichloro-2-methyl-6-(trifluoromethyl)pyrimidine; 6-Trifluoromethyl-4,5-dichloro-2-methylpyrimidine; Pyrimidine, 4,5-dichloro-2-methyl-6-(trifluoromethyl)-; 425394-33-8; 2-Methyl-4,5-dichloro-6-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Our 4,5-Dichloro-2-Methyl-6-Trifluoromethylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.