Description

5'-Amino-2'-Fluorobiphenyl-2-Carbonitrile is a high-purity fluorinated biphenyl derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a nitrile group on a fluorinated biphenyl scaffold, makes it an invaluable intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and other targeted therapy research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a core structure for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional polymers.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes for biological imaging and diagnostics.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5'-Amino-2'-Fluorobiphenyl-2-Carbonitrile
CAS No.	425378-70-7
Molecular Formula	C₁₃H₉FN₂
Molecular Weight	212.22 g/mol
Synonyms	2'-Fluoro-5'-aminobiphenyl-2-carbonitrile; [1,1'-Biphenyl]-2-carbonitrile, 5-amino-2'-fluoro-; 2'-Fluoro-5'-aminodiphenyl-2-carbonitrile; 5-Amino-2'-fluorobiphenyl-2-carbonitrile; 2-Cyano-2'-fluoro-5-aminobiphenyl; 2'-Fluoro-5'-amino-[1,1'-biphenyl]-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 5'-Amino-2'-Fluorobiphenyl-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply of high-grade material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.