Description

Pyrido[4,3-D]Pyrimidine, 5,6,7,8-Tetrahydro-2-Methyl-, Dihydrochloride is a high-purity, heterocyclic organic compound primarily utilized as a key pharmaceutical intermediate and research chemical. Its value lies in its role as a sophisticated building block for the synthesis of complex molecules, particularly in medicinal chemistry for drug discovery and development. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new bioactive compounds.
• Biochemical Research: Serves as a tool compound or precursor in biochemical assays and proteomics research.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic Research: Utilized in university and institutional labs for organic synthesis methodology development and chemical biology projects.
• Contract Research & Manufacturing (CRO/CMO): A key material for organizations providing custom synthesis and process development services.

Basic Information

Product Name	Pyrido[4,3-D]Pyrimidine, 5,6,7,8-Tetrahydro-2-Methyl-, Dihydrochloride
CAS No.	424819-91-0
Molecular Formula	C8H13N3 · 2HCl
Molecular Weight	240.13 g/mol (Free base: 167.21 g/mol)
Synonyms	2-Methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine dihydrochloride; 5,6,7,8-Tetrahydro-2-methylpyrido[4,3-d]pyrimidine dihydrochloride; 2-Methyl-4,5,6,7-tetrahydropyrido[4,3-d]pyrimidine dihydrochloride; 2-Methyl-4,5,6,7-tetrahydro-1H-pyrido[4,3-d]pyrimidine dihydrochloride; CAS 424819-91-0; 2-Methyl-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine HCl; 2-Methyl-4,5,6,7-tetrahydro-1H-pyrido[4,3-d]pyrimidine hydrochloride (1:2)
EINECS	Contact for details

Quality Control

Our Pyrido[4,3-D]Pyrimidine, 5,6,7,8-Tetrahydro-2-Methyl-, Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and purity, residual solvent analysis, and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.