Description

2-Methyl-6,7-Dihydro-5H-Pyrrolo[3,4-D]Pyrimidine Hydrochloride is a high-purity heterocyclic building block and pharmaceutical intermediate of significant commercial interest. Its pyrrolopyrimidine core structure makes it a valuable scaffold for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Serves as a versatile core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and process development stages for potential new chemical entities (NCEs).
• Biochemical Research: Employed as a reference standard or probe compound in biochemical and pharmacological assays.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the life sciences industry.

Basic Information

Product Name	2-Methyl-6,7-Dihydro-5H-Pyrrolo[3,4-D]Pyrimidine Hydrochloride
CAS No.	424819-90-9
Molecular Formula	C7H10N3Cl
Molecular Weight	171.63 g/mol
Synonyms	2-Methyl-5,6,7,8-tetrahydropyrrolo[3,4-d]pyrimidine hydrochloride; 2-Methyl-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine HCl; Pyrrolo[3,4-d]pyrimidine, 2-methyl-6,7-dihydro-5H-, hydrochloride; 424819-90-9; 2-Methyl-5,6,7,8-tetrahydropyrrolo[3,4-d]pyrimidine HCl salt; 2-Methyl-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine monohydrochloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-6,7-Dihydro-5H-Pyrrolo[3,4-D]Pyrimidine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by HPLC, NMR, and mass spectrometry. We adhere to cGMP principles for pharmaceutical intermediates, and custom synthesis and purification to meet specific project requirements are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.