Description

Prokineticin 2 Isoform 2 (Human) Trifluoroacetate Salt is a high-purity, biologically active peptide used in advanced life science research and pharmaceutical development. This compound is critical for studying its role as a signaling molecule in various physiological and pathological processes, including circadian rhythm regulation, angiogenesis, and neuroinflammation. It is an essential reagent for researchers and developers in academic institutions, biotechnology companies, and pharmaceutical R&D laboratories focusing on GPCR signaling, neurobiology, and metabolic disorders.

Application

• Biomedical Research: Fundamental studies on the biological functions and signaling pathways of Prokineticin 2 (PK2) and its receptors (PKR1 and PKR2).
• Drug Discovery & Development: Screening and validation of potential therapeutic agents targeting the Prokineticin system for conditions like obesity, diabetes, and inflammatory diseases.
• Cell-Based Assays: Used as a reference standard or active ligand in cell culture experiments to investigate receptor activation, downstream effects, and cellular responses.
• Neuroscience Research: Exploration of PK2's role in the central nervous system, including its effects on neuronal survival, neurogenesis, and circadian clock regulation.
• Angiogenesis Studies: Investigation of the peptide's pro-angiogenic properties in cancer research and vascular biology.
• In Vitro Diagnostics (IVD) Development: Potential use as a calibrator or component in assay development for research-use-only (RUO) test kits.

Basic Information

Product Name	Prokineticin 2 Isoform 2 (Human) Trifluoroacetate Salt
CAS No.	423206-00-2
Molecular Formula	C147H239N45O44S2 • xC2HF3O2
Molecular Weight	~3320.8 g/mol (Free base)
Synonyms	PK2; Prokineticin-2; PROK2; Bv8 (Human); Endocrine-Gland-Derived VEGF (EG-VEGF) Homolog; Z4 Protein; hPK2; Prokineticin 2 Isoform 2; Human Prokineticin-2 (81 AA); Prokineticin 2 (Human) Trifluoroacetate Salt
EINECS	Contact for details

Quality Control

Our Prokineticin 2 Isoform 2 (Human) Trifluoroacetate Salt is manufactured under stringent conditions to ensure the highest standards of purity and biological activity, suitable for sensitive research applications. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and endotoxin level testing. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every order to guarantee traceability, consistency, and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store the lyophilized powder under desiccant. After reconstitution, aliquot and store frozen at -80°C. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Sequence	AVITGA… (81 AA, Human PK2 Isoform 2)
Molecular Weight	3320.8 ± 2.0 Da (Monoisotopic, Free base)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10%
Endotoxin Level	< 1.0 EU/μg
Biological Activity	Determined by cell-based assay (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.