Description

4-Chloro-6-(4-Fluorophenyl)Pyrimidin-2-Amine is a high-purity pyrimidine derivative, a crucial building block in modern organic synthesis. This compound matters for its role as a key intermediate in the development of advanced pharmaceuticals and agrochemicals, enabling the creation of molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for constructing more complex pyrimidine-based compounds in academic and industrial research laboratories.
• Material Science Precursor: Potential use in the development of organic electronic materials and ligands for catalytic systems.

Basic Information

Product Name	4-Chloro-6-(4-Fluorophenyl)Pyrimidin-2-Amine
CAS No.	423183-88-4
Molecular Formula	C10H7ClFN3
Molecular Weight	223.63 g/mol
Synonyms	2-Amino-4-chloro-6-(4-fluorophenyl)pyrimidine; 4-Chloro-6-(p-fluorophenyl)-2-pyrimidinamine; 6-(4-Fluorophenyl)-4-chloropyrimidin-2-amine; 4-Chloro-6-(4-fluorophenyl)-2-aminopyrimidine; 2-Pyrimidinamine, 4-chloro-6-(4-fluorophenyl)-; 423183-88-4; 4-Chloro-6-(4-fluorophenyl)pyrimidin-2-ylamine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(4-Fluorophenyl)Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.