Description

Methyl 4-Oxo-2-Thioxo-1,2,3,4-Tetrahydro-Quinazoline-7-Carboxylate CAS NO 422277-15-4 is a high-purity, heterocyclic organic compound belonging to the quinazolinone class. This advanced pharmaceutical intermediate is critical for research and development in medicinal chemistry, offering a versatile scaffold for synthesizing novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinazolinone-based drug candidates with potential biological activity.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies to explore new therapeutic pathways.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization and the creation of complex heterocyclic libraries.
• Biochemical Research: Potential use in developing enzyme inhibitors or receptor modulators for biochemical assays.
• Academic Research: Employed in university and institutional labs for advanced organic synthesis and chemical methodology development.

Basic Information

Product Name	Methyl 4-Oxo-2-Thioxo-1,2,3,4-Tetrahydro-Quinazoline-7-Carboxylate
CAS No.	422277-15-4
Molecular Formula	C11H10N2O3S
Molecular Weight	250.27 g/mol
Synonyms	Methyl 4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylate; 7-Quinazolinecarboxylic acid, 1,2,3,4-tetrahydro-4-oxo-2-thioxo-, methyl ester; Methyl 1,2,3,4-tetrahydro-4-oxo-2-thioxoquinazoline-7-carboxylate; 422277-15-4; Quinazolinone derivative; 2-Thioxo-1,2,3,4-tetrahydro-4-oxoquinazoline-7-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Oxo-2-Thioxo-1,2,3,4-Tetrahydro-Quinazoline-7-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC and NMR, to meet exacting research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.