Description

9-(4-Methoxyphenyl)-6,6-Dimethyl-5,6,7,9-Tetrahydro-[1,2,4]Triazolo[5,1-B]Quinazolin-8(4H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazoloquinazolinone class of heterocyclic compounds. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate to develop new drug candidates with potential enhanced efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel drug candidates, particularly in neurological and psychiatric research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex heterocyclic scaffolds with potential biological activity.
• Research & Development (R&D): Essential for academic and industrial research programs focused on triazoloquinazolinone chemistry and pharmacology.
• API Synthesis: Employed in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) requiring this specific fused ring system.
• Biochemical Tool Compound: May serve as a reference standard or probe in biochemical assays to study specific enzyme or receptor interactions.

Basic Information

Product Name	9-(4-Methoxyphenyl)-6,6-Dimethyl-5,6,7,9-Tetrahydro-[1,2,4]Triazolo[5,1-B]Quinazolin-8(4H)-One
CAS No.	421586-23-4
Molecular Formula	C20H22N4O2
Molecular Weight	350.42 g/mol
Synonyms	9-(4-Methoxyphenyl)-6,6-dimethyl-4,5,6,7,9,10-hexahydro-[1,2,4]triazolo[5,1-b]quinazolin-8-one; 6,6-Dimethyl-9-(4-methoxyphenyl)-5,6,7,9-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-8(4H)-one; [1,2,4]Triazolo[5,1-b]quinazolin-8(4H)-one, 9-(4-methoxyphenyl)-6,6-dimethyl-5,6,7,9-tetrahydro-; CAS 421586-23-4
EINECS	Contact for details

Quality Control

Our 9-(4-Methoxyphenyl)-6,6-Dimethyl-5,6,7,9-Tetrahydro-[1,2,4]Triazolo[5,1-B]Quinazolin-8(4H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.